Metformin vs. Berberine – Which Medication Is Better for Diabetes

Even though type 2 diabetes doesn’t have a cure, several treatments and lifestyle changes can make a big difference. Aside from a healthy diet and plenty of exercises, patients with type 2 diabetes usually benefit from medication and insulin treatment. However, some diabetes medication comes with a number of side effects, and in many cases, it can do more harm than good.

Read on to find out more.


Metformin is a drug used to control high blood sugar, and it’s typically prescribed to patients with type 2 diabetes. It increases insulin sensitivity and lowers the production of glucose in the liver. While metformin is an effective blood sugar-lowering drug, it has many side effects. This includes bloating, weight gain, diarrhea, and nausea. Another side effect is vitamin B12 reduction, which increases the chances of neuropathy. In rare cases, it can even lead to lactic acidosis, which is a life-threatening condition.


Berberine is a bioactive plant extract that comes from traditional Chinese medication. It’s considered a healthier alternative to type 2 diabetes medication. This natural supplement has several powerful health benefits. It can decrease insulin resistance, lower blood sugar levels, and minimize glucose production in the liver. What’s more, berberine has anti-inflammatory properties that can help with weight loss and even improve heart health. Berberine doesn’t come with all the adverse effects of metformin, except for minor digestion issues. It’s generally seen as a safe treatment, as long as you take the recommended dosage and consult with your doctor.

Metformin vs. Berberine

While metformin is prescribed to many patients with type 2 diabetes, berberine is a safer and healthier option. Not only can berberine benefit diabetes patients, but also those who have high levels of cholesterol and high blood pressure. It can also be used for other health issues and conditions, such as gastrointestinal infections, fatty liver, certain infections, and even types of cancer.

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